
Dermatite Atopique - Modèles et tests pour
la recherche et l'évaluation de composés



LABORATOIRE DE RECHERCHE SOUS CONTRAT
Pharmacologie in vitro, ingénierie cellulaire, bioanalyses, développement de protocoles

COSMÉTIQUE
Etudes d’efficacité in vitro et ex vivo des produits cosmétiques : peau grasse, peau sèche, hydratation, vieillissement de la peau, pigmentation, etc.

DERMATOLOGIE
Tests d'efficacité et modèles in vitro pour la recherche préclinique : psoriasis, dermatite atopique, cicatrisation, acné, alopécie, pigmentation, etc.

PHARMACOLOGIE
Etudes d’efficacité in vitro et ex vivo des produits pharmaceutiques : immuno-inflammation, neurobiologie, médecine vétérinaire
POSTS ET PUBLICATIONS
Comparative analysis of original face and skin-warped average face images for the scoring of skin attributes
Cosmetics, Cosmetics, CosmétiqueNeryl acetate, the major component of Corsican Helichrysum italicum essential oil, mediates its biological activities on skin barrier
Barrière cutanée et hydratation, Cosmetics, Cosmetics, Cosmétique, Expression de gènes, Skin barrier and hydrationEvaluation of a new connected portable camera for the analysis of skin microrelief and the assessment of the effect of skin moisturisers
Cosmetics, Cosmetics, CosmétiqueAnalysis of correlation and construction of a predictive model of skin transparency using parameters from digital images of the face
Cosmetics, Cosmetics, CosmétiqueA novel clinical method to measure skin staining reveals activation of skin damage pathways by cigarette smoke
Cosmetics, Cosmetics, CosmétiqueMetrology and sensors as dermo-cosmetic technology opportunities for a change of paradigm
Cosmétique, DermatologieType-1 cytokines regulate MMP-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo
Pigmentation, PigmentationProfiling TLR agonist activity in keratinocytes and link to bacteria-induced innate immunity activation
Cosmetics, Microbiome cutané, Microbiome cutanéInnate immunity activation of sebocyte cells by living bacteria. Evidence of a potential immunosuppressive effect of DHT.
Acne, Acné, Microbiome cutané, Microbiome cutané, Microbiome cutané, Sebaceous gland regulationAndrogens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line.
Acne, Acné, Peau grasse, hyperséborrhée et séborégulation, Sebaceous gland regulationPollution and epigenetics: Histone H3 modifications in keratinocytes after exposure to urban dust and Benzo(a)pyrene
Cosmetics, Cosmetics, Cosmétique, Skin protection and immune defense systemRefined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin
Barrière cutanée et hydratation, Médecine vétérinaire, Skin barrier and hydration, Veterinary medicinePseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis
Cosmétique, Microbiome cutané, Microbiome cutanéNew Biological Activities of Lythrum salicaria L.
Barrière cutanée et hydratation, Cosmetics, Cosmétique, Skin barrier and hydrationEffects of different kinds of pollutants on the lipidic metabolism of human sebocytes and protective effects of a new macroalgae culture extract
Cosmetics, Peau grasse, hyperséborrhée et séborégulation, Protection et défenses cutanées, Sebaceous gland regulation, Skin protection and immune defense systemAcné vulgaris : Physiopathologie et mécanismes cellulaires
Acné, Peau grasse, hyperséborrhée et séborégulationLa glande sébacée : Physiologie et fonctions
Acné, Barrière cutanée et hydratation, Peau grasse, hyperséborrhée et séborégulationA Compensating Skin Care Complex Containing Pro-xylane in Menopausal Women: Results from a Multicentre, Evaluator-blinded, Randomized Study
Cosmetics, Cosmetics, CosmétiqueNew biological effects of Aphloïol
Barrière cutanée et hydratation, Cosmetics, Cosmétique, Skin barrier and hydrationin vitro modeling of skin photoaging: development of evaluation tools for cosmetics
Cosmetics, Skin ageing, Vieillissement cutanéDevelopment of a new model of reconstructed aged skin useful to study antiageing effects of cosmetic compounds
Cell and tissue engineering, Ingénierie cellulaire et tissulaire, Skin ageing, Vieillissement cutanéRab11a Is Essential for Lamellar Body Biogenesis in the Human
Barrière cutanée et hydratation, Skin barrier and hydrationExploration of scalp surface lipids reveals squalene peroxide as a potential actor in dandruff condition
CheveuxAndrogens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor
Acné, Acne, Cell and tissue engineering, Ingénierie cellulaire et tissulaire, Sebaceous gland regulation, Vieillissement cutanéEffect of C-xyloside on morphogenesis of the dermal epidermal junction in aged female skin. An ultrastuctural pilot study
Cosmetics, Cosmétique, Skin ageing, Vieillissement cutanéLipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (Sinetrol) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-Phosphodiesterase (PDE)
Adipocyte metabolism, Cosmetics, Cosmétique, Métabolisme adipocytaireReduced expression of the adhesion protein tensin1 in cultured human dermal fibroblasts affects collagen gel contraction
Cosmetics, Cosmétique, Skin ageing, Vieillissement cutanéAlternative (non-animal) methods for cosmetic testing: current status and future prospects – UV-induced effects
Cosmetics, Cosmétique, Protection et défenses cutanées, Safety and toleranceAlternative (non-animal) methods for cosmetic testing: current status and future prospects – Acute toxicity
Cosmetics, Cosmétique, Protection et défenses cutanées, Safety and toleranceComparison of gene expression profiles in human keratinocyte mono-layer cultures, reconstituted epidermis and normal human skin; transcriptional effects of retinoid treatments in reconstituted human epidermis
Cosmetics, Cosmétique, Epidermal regeneration, Régénération épidermiqueDevelopment of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis
Protection et défenses cutanées, Safety and toleranceAutologous Th2-polarized lymphocytes induce atopic dermatitis lesions in non-atopic human skin xenotransplants
Atopic dermatitis, Dermatite atopique, Pharmacologie, PharmacologyMalassezia restricta-mediated Lipoperoxidation: A Novel Trigger in Dandruff
Dermatologie, Dermatology, Hair follicleMetrology and sensors as dermo-cosmetic technology opportunities for a change of paradigm
Cosmétique, DermatologieProfiling TLR agonist activity in keratinocytes and link to bacteria-induced innate immunity activation
Cosmetics, Microbiome cutané, Microbiome cutanéFibroblasts are potentially the key sensors of epidermis lesion through keratinocyte IL-1 signalling
Cicatrisation, DermatologieInnate immunity activation of sebocyte cells by living bacteria. Evidence of a potential immunosuppressive effect of DHT.
Acne, Acné, Microbiome cutané, Microbiome cutané, Microbiome cutané, Sebaceous gland regulationPharmacological effects of anti-androgens and other compounds in an androgen-sensitive sebocyte cell line.
Acne, Acné, Sebaceous gland regulationAndrogens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line.
Acne, Acné, Peau grasse, hyperséborrhée et séborégulation, Sebaceous gland regulationOncostatin M is overexpressed in skin squamous-cell carcinoma and promotes tumor progression
DermatologiePseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis
Cosmétique, Microbiome cutané, Microbiome cutanéAcné vulgaris : Physiopathologie et mécanismes cellulaires
Acné, Peau grasse, hyperséborrhée et séborégulationLa glande sébacée : Physiologie et fonctions
Acné, Barrière cutanée et hydratation, Peau grasse, hyperséborrhée et séborégulationInterleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
Psoriasis, PsoriasisA skincare combined with combination of adapalene and benzoyl peroxide provides a significant adjunctive efficacy and local tolerance benefit in adult women with mild acne
Acné, AcneImiquimod-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome
Psoriasis, PsoriasisAndrogens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor
Acné, Acne, Cell and tissue engineering, Ingénierie cellulaire et tissulaire, Sebaceous gland regulation, Vieillissement cutanéStudy of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children
Cicatrisation, Wound healingEpidermal healing in burns: autologous keratinocyte transplantation as a standard procedure: update and perspective
Cicatrisation, Wound healingInhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1α, TNFα and oncostatin M
Inflammation, Inflammation, Psoriasis, PsoriasisContribution of IL22 to experimental skin inflammation
Inflammation, Inflammation, Psoriasis, PsoriasisForeskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts
Cicatrisation, Wound healingKeratinocytes under fire of proinflammatory cytokines: Bonafide innate immune cells involved in the physiopathology of chronic atopic dermatitis and psoriasis
Atopic dermatitis, Dermatite atopique, Psoriasis, PsoriasisImmortalized sebocytes SEBO662 can spontaneously differentiate into a sebaceous-like phenotype when cultured as a 3D epithelium
Acne, Acné, Cell and tissue engineering, Ingénierie cellulaire et tissulaire, Sebaceous gland regulationQuantitative and qualitative study in keratinocytes from foreskin in children: Perspective application in paediatric burns
Cicatrisation, Wound healingSkin inflammation induced by the synergistic action of IL17A, IL22, OSM, IL1α and TNFα recapitulates some features of psoriasis
Psoriasis, PsoriasisCultured keratinocyte cells from foreskin and future application for burns in children
Cicatrisation, Wound healingKeratinocytes as targets for cytokines in skin inflammation
Acne, Acné, Atopic dermatitis, Dermatite atopique, Dermatologie, Dermatology, Psoriasis, PsoriasisCytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils
Psoriasis, PsoriasisOSM (Oncostatin M) secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation
Psoriasis, PsoriasisKeratinocytes as targets for IL10-related cytokines : a putative role in psoriasis pathogenesis
Psoriasis, PsoriasisStimulation of the proliferation of human dermal fibroblasts in vitro by a lipidocolloid dressing
Cicatrisation, Wound healingIL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes
Inflammation, Inflammation, Psoriasis, PsoriasisExpression of type 1 5-alpha-reductase and metabolism of testosterone in reconstructed human epidermis
Acne, Acné, Dermatologie, DermatologyAutologous Th2-polarized lymphocytes induce atopic dermatitis lesions in non-atopic human skin xenotransplants
Atopic dermatitis, Dermatite atopique, Pharmacologie, PharmacologyPerformance and Tolerance of a Protocol for Idiopathic Chronic Greasy Seborrhea in 18 Dogs Using a Shampoo and Mousse Containing Plant Extracts
Médecine vétérinaire, Veterinary medicineDermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes
Inflammation, Pharmacologie, PharmacologyClinical and Microbiological Performances and Effects on Lipid and Cytokine Production of a Ceruminolytic Ear Cleaner in Canine Erythemato-Ceruminous Otitis Externa
Médecine vétérinaire, Veterinary medicineMultiplex Cytokine Analyses in Ear Canals of Dogs Suggest Involvement of IL-8 Chemokine in Atopic Otitis and Otodectic Mange—Preliminary Results
Médecine vétérinaire, Veterinary medicineLymphotonic activity of Ruscus extract, hesperidin methyl chalcone and vitamin C in human lymphatic smooth muscle cells
Pharmacologie, PharmacologySurvey of cytokines on ocular surfaces of atopic dogs by multiplex analysis using two sampling methods – a pilot Study
Médecine vétérinaire, Veterinary medicineEffets sur les signes cliniques, les lipides et les facteurs d’hydratation des applications combinées de shampooing et de mousse contenant de l’Ophytrium et du Seboliance chez les chiens atteints de séborrhée
Médecine vétérinaireÉvaluation des effets anti-inflammatoires et immunomodulateurs d’un produit sur un modèle in vitro de sang total canin
Médecine vétérinaireAddress
QIMA Life Sciences
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Latest posts
Cosmétique
- Hydratation et barrière cutanée
- Régénération épidermique
- Fermeté et cohésion de la peau
- Anti-âge et vieillissement cutané
- Protection et défenses cutanées
- Pigmentation cutanée
- Peau grasse et hyperséborrhée
- Amincissants et métabolisme adipocytaire
- Microcirculation cutanée et vascularisation
- Repousse des cheveux et alopécie