Immune-Inflammation

We collaborate closely with our clients

to build a healthier future.

Research Areas

Cell & Tissue Damage

  • Acute inflammation or stress
  • Chronic inflammation, stress or disease
  • Defense mechanisms & Epithelial barrier response against damage and ageing
  • Regulation of immuno-inflammatory responses

Tissue Regeneration

  • Tissue repair
  • Wound healing

Immune Cells

Discover our

Human Mast Cell model

Primary cells

(human)
  • Granulocytes (PMNs)
  • Neutrophils
  • Eosinophils
  • Basophils
  • T lymphocytes
  • B lymphocytes
  • Monocytes
  • Macrophages
  • Dendritic cells
  • Mast cells

Primary cells

(murine)
  • Splenocytes
  • Thymocytes
  • Mast cells

Whole Blood

(human)

More information here

Cell lines 

(human)
  • U937
  • THP1
  • HL-60
  • Jurkat

Ex vivo models

(human)
  • skin explants
  • hair explants
  • Co-culture of human hair follicles with autologous primary immune cells (CD8+ T-cells, CD4+ T-cells, gamma delta T-cells, etc.)

In vivo models

  • humanized-mouse models

Assays

  • PMN, Macrophage, Dendritic Cell activation
  • Phagocytosis
  • PMN oxidative burst
  • M1 or M2 polarization and switch
  • Chemotaxis
  • T cell differentiation
  • Treg phenotyping
  • Proliferation
  • Cytokine and chemokine production and release
  • Expression of cytokine and chemokine receptors
  • Immune cell phenotype
  • Regulation of skin and hair follicle physiology
  • Number of immune cells in specific skin or hair follicle compartments

Learn more about our

Immune Response Assays

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