Vet. Sci. 2023, 10, 95

KONDRATJEVA J., BRUN J., AMALRIC N., MOOG F., COMBARROS D., PRESSANTI C., ZEMIRLINE C., MAUBERT N., OLLIVIER E., GATELLET M., CADIERGUES MC. (2023)

Small Animal Clinic, Université de Toulouse, ENVT, 31076 Toulouse, France.
INFINITy, Université de Toulouse, Inserm, CNRS, UPS, 31059 Toulouse, France.
Ceva Santé Animale, 53950 Louverné, France
Ceva Santé Animale, 33500 Louverné, France
QIMA Life Sciences, Labège, France.

Abstract

The study aimed to evaluate the tolerance, performance and effect on hair lipids and skin hydration of a protocol combining applications of one shampoo and subsequent mousses containing plant extracts (Ophytrium and Seboliance) in dogs with an undiagnosed chronic greasy keratinisation disorder. Six dogs were washed with plain water on day (D)0. Twelve dogs were shampooed on D0 and received eight mousse applications at 48–72 h intervals from D2 to D18. Clinical score (CS), Natural Moisturizing Factors (NMF) and hair lipids (HL) were evaluated on D0, D0 + 4 h, D7, D14 and D24. At baseline, no significant differences were observed in CS, NMF and HL between groups. In the control group, CS and HL remained stable throughout the study while a slight decrease in NMF was observed at D0 + 4 h. CS was significantly reduced in the test group between D0 and D7 (-53%) which reached 91% at D24 (p < 0.05), with no side effects. NMF levels decreased in the test group at D0 + 4 h (-73%, p < 0.0001) and returned to baseline from D14. In conclusion, one shampoo and subsequent mousse applications rapidly and safely improved coat quality in dogs with an undiagnosed keratinisation disorder without affecting NMF and HL contents over the study period.

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KEYWORDS: canine; skin; seborrhea; shampoo; mousse; Ophytrium; Seboliance