| Year | Title | Author | Journal | Link | Conference |
|---|---|---|---|---|---|
| 2024 | Using comparative transcriptomic profiling ex vivo to identify novel, potential targets for acute and chronic wound healing | Ilaria Piccini, Markus Fehrholz, Ralf J. Ludwig, John Ziber, Jan Alenfall, Anna Hultgårdh, Jan Nilsson, Ralf Paus, Marta Bertolini | download presentation | European Academy of Dermatology & Venereology (EADV) Abstract No. 4410 |
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| 2024 | Unravelling Insights into the Mechanism of Action of Secukinumab in Ameliorating the Inflammatory Phenotype of Hidradenitis Suppurativa: Lessons from Diseased Skin Organ Culture | J Edelkamp, A Pal, J Viola-Söhnlein, M Fehrholz, E Nicodeme, F Bechara, S Schneider-Burrus, V Julia, K Pappelbaum, M Bertolini | download poster | European Hidradenitis Suppurativa Foundation Abstract No. 241 |
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| 2023 | Exploring the role of interleukin 15 in atopic dermatitis: Lesson from a humanized mouse model > Abstract Award of the ISDS 2023 | l Piccini, O Egriboz, A Keren, A Pal, K Pappelbaum, A Gilhar, A Vicari, M Bertolini | JID | read the full story download poster | Inflammatory Skin Disease Summit (ISDS) Abstract No. 132 |
| 2023 | Preclinical Ex Vivo and In Vivo Evidence Supporting Selective Inhibition of Tyrosine Kinase 2-Dependent, IL-12-Mediated Signaling as a Novel Pharmacological Strategy for Alopecia Areata Management | J Edelkamp, T Rouille, J H Kim, A Keren, J V Söhnlein, L Gao, A Rossi, F Jimenez, A Gilhar, R Paus, I M. Catlett, M Bertolini | JID | read the full story | Inflammatory Skin Disease Summit (ISDS) Abstract No. 27 |
| 2023 | Short-term IL-23 neutralization reduces IL-23 transcription and number of activated pro-inflammatory mononuclear phagocyte (MNPs) in psoriasis skin ex vivo | L Zondler, M Lousada, Y Skabytska, K I Pappelbaum, M V Lessen, M Fehrholz, A Tsianakas, M Bertolini | JID | read the full story | Inflammatory Skin Disease Summit (ISDS) Abstract No. 133 |
| 2023 | Regulatory gd T cells protect human scalp hair follicles from alopecia areata in vivo | A Keren, N Goldstein, M Bertolini, R Kassem, R Paus, A Gilhar | JID | read the full story | Inflammatory Skin Disease Summit (ISDS) Abstract No. 185 |
| 2023 | Perceived stress can trigger psoriatic lesions in human skin in vivo, which can be suppressed by aprepitant | A Keren, A A Zeltzer, R Paus, A Gilhar | JID | read the full story | Inflammatory Skin Disease Summit (ISDS) Abstract No. 170 |
| 2023 | A novel ex vivo model of human hair follicle immune privilege collapse reveals the therapeutic potential of DHODH inhibition by farudodstat for alopecia areata management | T Rouillé, S Barbosa, A Steinhoff, I Piccini, n Edelkamp, A Kaoukhov, C Firth, F Cevikbas, M Bertolini | JID | read the full story | Inflammatory Skin Disease Summit (ISDS) Abstract No. 90 |
| 2023 | Pre-clinical in-vitro assays for high throughput screening of drug candidates for protection and restoration of immune privilege in alopecia areata | P Pallavi, A Le Riche, M van Lessen, P Scheipers, A Herchenhan, T Bíro, M Bertolini | JID | read the full story | International Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1419 |
| 2023 | Characterization of the human scalp hair follicle microbiome reveals differential spatial distribution, abundance and viability of intrafollicular microbiota and modulation of hair growth and metabolism by Staphylococcus epidermidis | MB Lousada, J Edelkamp, T Lachnit, F Jimenez, TCG Bosch, R Paus | JID | read the full story | International Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1032 |
| 2023 | Ashwagandha-derived exosome-like nanoparticles promote human hair growth ex vivo | A Le Riche, J Nienhaus, M Sousa, R Scotland, M Bertolini, G Dell‘ Acqua, J Edelkamp | JID | read the full story | International Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1420 |
| 2023 | Estetrol Prolongs Anagen in healthy female scalp hair follicles by Positively Modulating Dermal Papilla Functions and generation of Progenitor Stem Cells Ex Vivo | A Le Riche, S Altendorf, V Dion, C Gerard, T Bíro, G Dixon, M Bertolini | JID | read the full story | International Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1386 |
| 2023 | IL-15 contributes to atopic dermatitis pathogenesis: lessons from a novel humanized mouse disease model | I Piccini, O Egriboz, A Pal, KI Pappelbaum, M Fehrholz, A Keren, R Paus, A Gilhar, A Vicari, M Bertolini | JID | read the full story | International Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 55 |
| 2023 | Activation of the olfactory receptor 2A4/7 with the odorant cyclohexyl salicylate prolongs anagen and stimulates hair follicle stem cell progeny expansion | J Edelkamp, D Pinto, H Erdmann, T Purba, F Jimenez, R Paus, M Bertolini | Exp. Dermatol | read the full story | Arbeitsgemeinschaft Dermatologische Forschung (ADF Tagung) Abstract Nr. P222 |
| 2023 | Testosterone exerts expected and unexpected responses ex vivo in hair follicles from affected and non affected scalp of androgenetic alopecia patients | S Altendorf, M Fehrholz, M Geyfman, N Poloso, F Jimenez, H Erdmann, T Bíró, R Paus, M Bertolini | Exp. Dermatol | read the full story | Arbeitsgemeinschaft Dermatologische Forschung (ADF Tagung) Abstract Nr. P221 |
| 2022 | Single-cell sequencing of freshly isolated cells from lesional and peri-lesional skin to explore cellular origins of IL-17 isoforms in psoriasis | A Skelton, K Pappelbaum, X Li, V Oji, A Tsianakas, M Page, M Bertolini, S Shaw, A Maroof | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract Nr. 038 |
| 2022 | Tyrosine kinase 2 inhibition rescues hair follicles from IL-12—mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse model | J Edelkamp, T Rouille, JH Kim, AKeren, J Viola-Söhnlein, L Gao, A Rossi, F Jimenez, A Gilhar, R Paus, M Bertolini, IM Catlett | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract Nr. 700 |
| 2022 | Charting the human hair follicle microbiome: Composition, distribution, and functional impact of the bacterial metabolite, butyrate | M Lousada, J Edelkamp, T Lachnit, M Fehrholz, H Erdmann, F Jimenez, R Paus | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 550 |
| 2022 | Treatment with cyclohexyl salicylate, an olfactory receptor 2A4/7 agonist, promotes human hair follicle growth and bulge stem cell progeny expansion | J Edelkamp, D Pinto, H Erdmann, T Purba, F Jimenez, M Bertolini, R Paus | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 732 |
| 2022 | Novel human skin organ culture models for the identification and characterization of anti-aging actives ex vivo | M van Lessen, A Mardaryev, C Mauri, W Funk, M Kückelhaus, J Edelkamp, R Paus, T Biró, | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 842 |
| 2022 | Hair follicles can “taste”: Stevioside stimulation of the bitter taste receptor TAS2R4 inhibits human hair growth ex vivo | J Gherardini, T Rouillé, M Fehrholz, W Funk, J Rodríguez-Feliz, A J. Bauman, T Biró, J Chéret, R Paus | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 743 |
| 2022 | Generation of laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlas | M Fehrholz, I Piccini, L Timperi, A Mardaryev, F Jimenez, D Pinto, F Rinaldi, R Paus, T Biró, M Bertolini | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 731 |
| 2022 | Exploring the synergistic effects of a plant extract and a peptide on hair follicle pigmentation. | D Broadley, M van Lessen, T Atsushi, A Ryohei, S Kazuhiro, A Akinari, N Tohru, T Akiko, W Funk, H Erdmann, T Biró, M Bertolini | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 640 |
| 2021 | Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo. | I Piccini, M Fehrholz, O Egriboz, L Ponce, A Rossi, F Jimenez, J Adams, CM Crosby and M Bertolini | J Invest Dermatol | read the full story download poster | European Society for Dermatological Research Abstract no. 020 |
| 2021 | Exploring the potential of the novel IFNg aptamer TAGX-0003 as a treatment for alopecia areata in pre-clinical models. | M Fehrholz , K Harada , I Piccini , A Gilhar , S Mutu and M Bertolini | J Invest Dermatol | read the full story download poster | European Society for Dermatological Research Abstract no. 022 |
| 2021 | Selective inhibition of tyrosine kinase 2 prevents and restores interleukin-12- induced hair follicle immune privilege collapse: a novel approach to alopecia areata therapy? | J Edelkamp , T Rouille , J Kim , A Rossi , F Jimenez , R Paus, I Catlett and M Bertolini | J Invest Dermatol | read the full story download poster | European Society for Dermatological Research Abstract no. 061 |
| 2021 | Laser-capture microdissection coupled to metagenomics: A powerful method for analysis of the HF microbiome. | M Lousada, J Edelkamp, T Lachnit, M Fehrholz, TG Bosch and R Paus | J Invest Dermatol | read the full story download poster | European Society for Dermatological Research Abstract no. 322 |
| 2021 | A novel cosmetic anti-hair loss approach: An extract of Leontopodium alpinum inhibits catagen development | J Edelkamp, R Campiche, A Le Riche, A Fernandez, M Gempeler, E Martin and M Bertolini | J Invest Dermatol | read the full story download poster | European Society for Dermatological Research Abstract no. 330 |
| 2021 | Poor perifollicular vascularization is associated with nutrient insufficiency and a quiescent metabolic phenotype in intermediate hair follicles from patients with female pattern hair loss | I Piccini, M Sousa, J Edelkamp, F Jimenez, A Rossi, R Paus and M Bertolini | J Invest Dermatol | read the full story download poster | European Society for Dermatological Research Abstract no. 333 |
| 2021 | Sphingosine 1-phosphate receptors are expressed in human scalp hair follicles and their modulation by etrasimod warrants further investigation for management of alopecia areata. | I Piccini, M Fehrholz, O Egriboz, L Ponce, JW Adams, CM Crosby, M Bertolini | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 489 |
| 2021 | Human skin organ culture permits to preclinically assess the effects of “UVfree tanning” and “skin lightening” agents on epidermal melanogenesis. | M van Lessen , T Biro , J Edelkamp, M Bertolini, R Paus | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 540 |
| 2021 | An extract of Leontopodium alpinum prolongs anagen phase in human hair follicles ex vivo | R Campiche, A Le Riche, J Edelkamp, E Martin, M Gempeler, M Bertolini | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 575 |
| 2021 | Hair follicle chemosensation: TRPM5 signaling is required for anagen maintenance | A Mardaryev , M van Lessen, FJ Acosta , T Biro, R Paus | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 589 |
| 2021 | Pre‐clinical trial platform for assessing the effect of cosmeceutical agents on epidermal melanogenesis in human skin organ culture. | M van Lessen, R Alqasemi, J Edelkamp, M Bertolini, R Paus, T Bíró | Exp Dermatol. | read the full story download poster | 47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung Abstract no. P174 |
| 2021 | Probing the morphogenic potential of human hair matrix keratinocytes in generating hair follicle organoids in vitro and ex vivo. | I Piccini, K Bakkar, C Collin‐Djangone, J Gherardini, R Paus, M Bertolini | Exp Dermatol. | read the full story download poster | 47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung Abstract no. P240 |
| 2021 | Application of topical Sandalore increases epidermal dermcidin synthesis in organ‐cultured human skin ex vivo. | J Edelkamp, D Pinto, J Chéret, J D B O’Sullivan, F Jimenez, W Funk, C Roessing, V Rippmann, F Rinaldi, R Paus, M Bertolini | Exp Dermatol. | read the full story download poster | 47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung Abstract no. P241 |
| 2021 | Hair follicle chemosensation: TRPM5 signaling is required for anagen maintenance. | A Mardaryev, M van Lessen, F Jimenez Acosta, R Paus, T Bíró | Exp Dermatol. | read the full story download poster | 47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung Abstract no. P245 |
| 2021 | A novel strategy for preventing chemotherapy‐induced permanent alopecia: PPARg signaling modulation protects from cyclophosphamide‐induced bulge stem cell apoptosis and epithelial‐mesenchymal transition ex vivo | I Piccini, J Chéret, S Ghatak1, M Alam, J Hardman, H Erdmann, F Jimenez, C Ward, R Paus, M Bertolini | Exp Dermatol. | read the full story download poster | 47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung Abstract no. P250 |
| 2019 | Mouse models of alopecia areata: C3H/HeJ mice versus the humanized AA mouse model. | A Gilhar, A Keren, R Paus | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 080 |
| 2019 | Which characteristics does an optimal animal model for psoriasis need to show? | A Gilhar, A Keren, R Paus | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 081 |
| 2019 | OR2AT4 activation by a synthetic odorant, stimulates dermcidin production in human hair follicle epithelium and increases follicular resistance to bacterial contamination: A novel antimicrobial folliculitis therapy? | J Lehmann, J Cheret, L Ponce, F Jimenez, H Eerdmann, M Bertolini, R Paus | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 495 |
| 2019 | Possible role of ILC1 in the pathogenesis of alopecia areata (AA). | R Laufer Britva, A Keren, Y Ullmann, R Paus, A Gihar | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 516 |
| 2019 | Topical Sandalore®, a specific OR2AT4-stimulating odorant, ameliorates female telogen effluvium: Randomized, double-blinded, placebo-controlled clinical trial. | M Bertolini, F Jimenez, E Lopez, M Alam, C Ward, J Cheret, G Westgate, F Rinaldi, R Paus | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 609 |
| 2019 | Development of a novel humanized mouse model for atopic dermatitis. | A Karen, C Reithmüller, Y Ullmann, R Paus, A Gilhar | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 661 |
| 2019 | PPARγ stimulation protects from cyclophosphamide-induced hair follicle cytotoxicity and bulge stem cell damage. | I Piccini, J Cheret, S Ghatak, M Alam, J Hardmann, H Erdmann, F Jimenez, C Ward, R Paus, M Bertolini | J Invest Dermatol | read the full story download poster | Society for Investigative Dermatology Abstract no. 909 |
| 2019 | Dermal white adipose tissue secretes hepatocyte growth factor to promote human hair follicle growth and pigmentation. | C Nicu, J Hardmann, T Lai, J Pople, R Bhogal, D Ansell, R Paus | J Invest Dermatol | read the story | Society for Investigative Dermatology Abstract no. 992 |
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