Conference Proceedings

We submit our scientific work to international publications and

conferences to actively contribute to advancing research in dermatology and trichology.

YearTitleAuthorJournalLinkConference
2024Using comparative transcriptomic profiling ex vivo to identify novel, potential targets for acute and chronic wound healingIlaria Piccini, Markus Fehrholz, Ralf J. Ludwig, John Ziber, Jan Alenfall, Anna Hultgårdh, Jan Nilsson, Ralf Paus, Marta Bertoliniread the full story
download presentation		European Academy of Dermatology & Venereology (EADV)
Abstract No. 4410
2024Treatment with USPlus®Derm prolongs anagen through positive modulation of dermal papilla inductivity and reinforces the hair follicle stem cell niche in organ cultured, occipital healthy male scalp hair folliclesDavid Broadley, Alizee Le Riche, Francisco Jimenez, Margaret Dohnalek, Janin Edelkamp, Marta Bertoliniread the full storyEuropean Academy of Dermatology & Venereology (EADV)
Abstract No. 4921
2024Using diseased skin organ culture to gain further insight into the mechanisms of Secukinumab in ameliorating the inflammatory phenotype of hidradenitis suppurativa lesionsJanin Edelkamp, Anasua Pal, Joana Viola-Söhnlein, Markus Fehrholz, Edwige Nicodeme, Falk Bechara, Sylke Schneider-Burrus, Valerie Julia, Karin Pappelbaum, Marta Bertoliniread the full storyEuropean Academy of Dermatology & Venereology (EADV)
Abstract No. 4919
2024Exploring the cross talk between mast cells and nerve fibers in photoaging in re-innervated skin ex vivoMarta Silva e Sousa, Moe Tsutsumi, Sofoklis Koudounas, Onur Egriboz, Wolfgang Funk, Maximilian Kückelhaus, Kentaro Kajiya, Ilaria Piccini, Marta Bertoliniread the full storyEuropean Academy of Dermatology & Venereology (EADV)
Abstract No. 4917
2024A Physiologically Relevant In Vitro Model for Acne Vulgaris: The SEBO662AR Sebocyte Cell LineSamuel Guenin, Ophélie Tutti, Fabienne Guyard, Guillaume Lecerf, Nathalie Pedretti, Lucie Lardeux, Aline Larrignon, Vincent Morin, Julien Oré, Laure Pasquer, Cécile Trespeuch, Séverine Thibaut De Ménonville, Valérie Hamon de Almeida, Nicolas Amalricread the full storyEuropean Academy of Dermatology & Venereology (EADV)
Abstract No. 4907
2024Image analysis, the correlation between color and roughness parameters and clinical evaluation of psoriatic lesions using a nomad camera (SkinCam)Claudia Angélica Cázares Núñez, Alejandro Castillo Martinez, Andrea Rodriguez Rios, Alix Danoy, Matthieu Jomierread the full storyEuropean Academy of Dermatology & Venereology (EADV)
Abstract No. 1918
2024Unbiased transcriptomic analysis of experimentally induced physiological and pathological skin wounds ex vivo reveals potential therapeutic targetsIlaria Piccini, Markus Fehrholz, Ralf J. Ludwig, John Ziber, Jan Alenfall, Anna Hultgårdh, Jan Nilsson, Ralf Paus, Marta Bertoliniread the full storyEuropean Society for Dermatological Research (ESDR)
Abstract No. 532
2024Understanding the mechanism of action of secukinumab using lesional hidradenitis suppurativa skin organ cultureJanin Edelkamp, Anasua Pal, Joana Viola-Söhnlein, Markus Fehrholz, Edwige Nicodeme, Falk Bechara, Sylke Schneider-Burrus, Valerie Julia, Karin Pappelbaum, Marta Bertoliniread the full storyEuropean Society for Dermatological Research (ESDR)
Abstract No. 496
2024Using the human iPSCs-derived sensory neurons re-innervated skin ex vivo model to investigate mast cell-nerve fiber cross-talk in solar elastosisMarta Silva e Sousa, Moe Tsutsumi, Sofoklis Koudounas, Onur Egriboz, Wolfgang Funk, Maximilian Kückelhaus, Kentaro Kajiya, Ilaria Piccini, Marta Bertoliniread the full storyEuropean Society for Dermatological Research (ESDR)
Abstract No. 509
2024Revealing Insights on IL-17A inhibition in Hidradenitis Suppurativa by diseased skin organ cultureJanin Edelkamp, Anasua Pal, Joana Viola-Söhnlein, Markus Fehrholz, Edwige Nicodeme, Falk Bechara, Sylke Schneider-Burrus, Valerie Julia, Karin Pappelbaum, Marta BertoliniJIDread the full storySociety for Investigative Dermatology (SID)
Abstract No. 420
2024Exploring Sebocyte Differentiation and Lipid Metabolism in Acne Vulgaris: A Study Using the SEBO662AR Cell Line ModelSamuel Guenin, Ophélie Tutti, Fabienne Guyard, Guillaume Lecerf, Nathalie Pedretti, Lucie Lardeux, Aline Larrignon, Vincent Morin, Julien Oré, Laure Pasquer, Cécile Trespeuch, Valérie Hamon de Almeida, Nicolas AmalricJIDread the full storySociety for Investigative Dermatology (SID)
Abstract No. 559
2024USPlus®Derm reinforces the stem cell niche and prolongs anagen by positively modulating dermal papilla inductivity in occipital male scalp hair folliclesDavid Broadley, Alizee Le Riche, Francisco Jimenez, Margaret Dohnalek, Janin Edelkamp, Marta BertoliniJIDread the full storySociety for Investigative Dermatology (SID)
Abstract No. 574
2024Identification of novel potential therapeutic targets by comparative transcriptomic profiling of physiological and pathological skin wounds ex vivoIlaria Piccini, Markus Fehrholz, Ralf J. Ludwig, John Ziber, Jan Alenfall, Anna Hultgårdh, Jan Nilsson, Ralf Paus, Marta BertoliniJIDread the full storySociety for Investigative Dermatology (SID)
Abstract No. 682
2024Investigating mast cell-nerve fiber cross-talk in photoaging using the human iPSCs-derived sensory neurons re-innervated skin ex vivo modelMarta Silva e Sousa, Moe Tsutsumi, Sofoklis Koudounas, Onur Egriboz, Wolfgang Funk, Maximilian Kückelhaus, Kentaro Kajiya, Ilaria Piccini, Marta BertoliniJIDread the full storySociety for Investigative Dermatology (SID)
Abstract No. LB966
2024Ashwagandha-derived exosome-like nanoparticles significantly promote human hair growth ex vivo and in vivo by stimulating the production of the anagen promoting growth factor VEGF-AAlizee Le Riche, Janina Nienhaus, Hanieh Erdmann, Ilaria Piccini, M.Bertolini, J. Edelkamp*, G. Dell‘ Acqua*JIDread the full storySociety for Investigative Dermatology (SID)
Abstract No. LB1010
2024T-cell receptor stimulation in human hair follicle organ culture leads to immune privilege collapse, which is prevented by farudodstat treatmentThomas Rouillé, Silvia Barbosa, Ana Steinhoff, Ilaria Piccini, Janin Edelkamp, Alexandre Kaoukhov, Carl Firth, Ferda Cevikbas, Marta BertoliniExp. Dermatol.read the full storyADF
Abstract No. 244
2024IL-15 neutralization results in the prevention/amelioration of skin barrier defects and pro-inflammatory environment in AD lesions experimentally induced in human xenotransplantsllaria Piccini, Onur Egriboz, Aviad Keren, Amos Gilhar, Alain Vicari, Marta BertoliniExp. Dermatol.read the full storyADF
Abstract No. 173
2024Unravelling Insights into the Mechanism of Action of Secukinumab in Ameliorating the Inflammatory Phenotype of Hidradenitis Suppurativa: Lessons from Diseased Skin Organ CultureJ Edelkamp, A Pal, J Viola-Söhnlein, M Fehrholz, E Nicodeme, F Bechara, S Schneider-Burrus, V Julia, K Pappelbaum, M Bertolinidownload posterEuropean Hidradenitis Suppurativa Foundation
Abstract No. 241
2023Exploring the role of interleukin 15 in atopic dermatitis: Lesson from a humanized mouse model
> Abstract Award of the ISDS 2023		l Piccini, O Egriboz, A Keren, A Pal, K Pappelbaum, A Gilhar, A Vicari, M BertoliniJIDread the full story
download poster		Inflammatory Skin Disease Summit (ISDS)
Abstract No. 132
2023Preclinical Ex Vivo and In Vivo Evidence Supporting Selective Inhibition of Tyrosine Kinase 2-Dependent, IL-12-Mediated Signaling as a Novel Pharmacological Strategy for Alopecia Areata ManagementJ Edelkamp, T Rouille, J H Kim, A Keren, J V Söhnlein, L Gao, A Rossi, F Jimenez, A Gilhar, R Paus, I M. Catlett, M BertoliniJIDread the full storyInflammatory Skin Disease Summit (ISDS)
Abstract No. 27
2023Short-term IL-23 neutralization reduces IL-23 transcription and number of activated pro-inflammatory mononuclear phagocyte (MNPs) in psoriasis skin ex vivoL Zondler, M Lousada, Y Skabytska, K I Pappelbaum, M V Lessen, M Fehrholz, A Tsianakas, M BertoliniJIDread the full storyInflammatory Skin Disease Summit (ISDS)
Abstract No. 133
2023Regulatory gd T cells protect human scalp hair follicles from alopecia areata in vivoA Keren, N Goldstein, M Bertolini, R Kassem, R Paus, A GilharJIDread the full storyInflammatory Skin Disease Summit (ISDS)
Abstract No. 185
2023Perceived stress can trigger psoriatic lesions in human skin in vivo, which can be suppressed by aprepitantA Keren, A A Zeltzer, R Paus, A GilharJIDread the full storyInflammatory Skin Disease Summit (ISDS)
Abstract No. 170
2023A novel ex vivo model of human hair follicle immune privilege collapse reveals the therapeutic potential of DHODH inhibition by farudodstat for alopecia areata managementT Rouillé, S Barbosa, A Steinhoff, I Piccini, n Edelkamp, A Kaoukhov, C Firth, F Cevikbas, M BertoliniJIDread the full storyInflammatory Skin Disease Summit (ISDS)
Abstract No. 90
2023Pre-clinical in-vitro assays for high throughput screening of drug candidates for protection and restoration of immune privilege in alopecia areataP Pallavi, A Le Riche, M van Lessen, P Scheipers, A Herchenhan, T Bíro, M BertoliniJIDread the full storyInternational Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1419
2023Characterization of the human scalp hair follicle microbiome reveals differential spatial distribution, abundance and viability of intrafollicular microbiota and modulation of hair growth and metabolism by Staphylococcus epidermidisMB Lousada, J Edelkamp, T Lachnit, F Jimenez, TCG Bosch, R PausJIDread the full storyInternational Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1032
2023Ashwagandha-derived exosome-like nanoparticles promote human hair growth ex vivoA Le Riche, J Nienhaus, M Sousa, R Scotland, M Bertolini, G Dell‘ Acqua, J EdelkampJIDread the full storyInternational Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1420
2023Estetrol Prolongs Anagen in healthy female scalp hair follicles by Positively Modulating Dermal Papilla Functions and generation of Progenitor Stem Cells Ex VivoA Le Riche, S Altendorf, V Dion, C Gerard, T Bíro, G Dixon, M BertoliniJIDread the full storyInternational Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 1386
2023IL-15 contributes to atopic dermatitis pathogenesis: lessons from a novel humanized mouse disease modelI Piccini, O Egriboz, A Pal, KI Pappelbaum, M Fehrholz, A Keren, R Paus, A Gilhar, A Vicari, M BertoliniJIDread the full storyInternational Societies for Investigative Dermatology: ISID Meeting Abstract Nr. 55
2023Activation of the olfactory receptor 2A4/7 with the odorant cyclohexyl salicylate prolongs anagen and stimulates hair follicle stem cell progeny expansionJ Edelkamp, D Pinto, H Erdmann, T Purba, F Jimenez, R Paus, M BertoliniExp. Dermatolread the full storyArbeitsgemeinschaft Dermatologische Forschung (ADF Tagung) Abstract Nr. P222
2023Testosterone exerts expected and unexpected responses ex vivo in hair follicles from affected and non affected scalp of androgenetic alopecia patientsS Altendorf, M Fehrholz, M Geyfman, N Poloso, F Jimenez, H Erdmann, T Bíró, R Paus, M BertoliniExp. Dermatolread the full storyArbeitsgemeinschaft Dermatologische Forschung (ADF Tagung) Abstract Nr. P221
2022Single-cell sequencing of freshly isolated cells from lesional and peri-lesional skin to explore cellular origins of IL-17 isoforms in psoriasisA Skelton, K Pappelbaum, X Li, V Oji, A Tsianakas, M Page, M Bertolini, S Shaw, A MaroofJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract Nr. 038
2022Tyrosine kinase 2 inhibition rescues hair follicles from IL-12—mediated immune privilege collapse and reverses the induction of human alopecia areata in a humanized mouse modelJ Edelkamp, T Rouille, JH Kim, AKeren, J Viola-Söhnlein, L Gao, A Rossi, F Jimenez, A Gilhar, R Paus, M Bertolini, IM CatlettJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract Nr. 700
2022Charting the human hair follicle microbiome: Composition, distribution, and functional impact of the bacterial metabolite, butyrateM Lousada, J Edelkamp, T Lachnit, M Fehrholz, H Erdmann, F Jimenez, R PausJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 550
2022Treatment with cyclohexyl salicylate, an olfactory receptor 2A4/7 agonist, promotes human hair follicle growth and bulge stem cell progeny expansionJ Edelkamp, D Pinto, H Erdmann, T Purba, F Jimenez, M Bertolini, R PausJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 732
2022Novel human skin organ culture models for the identification and characterization of anti-aging actives ex vivoM van Lessen, A Mardaryev, C Mauri, W Funk, M Kückelhaus, J Edelkamp, R Paus, T Biró,J Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 842
2022Hair follicles can “taste”: Stevioside stimulation of the bitter taste receptor TAS2R4 inhibits human hair growth ex vivoJ Gherardini, T Rouillé, M Fehrholz, W Funk, J Rodríguez-Feliz, A J. Bauman, T Biró, J Chéret, R PausJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 743
2022Generation of laser capture microdissection and RNAseq-based human anagen hair follicle transcriptome atlasM Fehrholz, I Piccini, L Timperi, A Mardaryev, F Jimenez, D Pinto, F Rinaldi, R Paus, T Biró, M BertoliniJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 731
2022Exploring the synergistic effects of a plant extract and a peptide on hair follicle pigmentation.D Broadley, M van Lessen, T Atsushi, A Ryohei, S Kazuhiro, A Akinari, N Tohru, T Akiko, W Funk, H Erdmann, T Biró, M BertoliniJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 640
2021Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo.I Piccini, M Fehrholz, O Egriboz, L Ponce, A Rossi, F Jimenez, J Adams, CM Crosby and M BertoliniJ Invest Dermatolread the full story
download poster		European Society for Dermatological Research Abstract no. 020
2021Exploring the potential of the novel IFNg aptamer TAGX-0003 as a treatment for alopecia areata in pre-clinical models.M Fehrholz , K Harada , I Piccini , A Gilhar , S Mutu and M BertoliniJ Invest Dermatolread the full story
download poster		European Society for Dermatological Research Abstract no. 022
2021Selective inhibition of tyrosine kinase 2 prevents and restores interleukin-12- induced hair follicle immune privilege collapse: a novel approach to alopecia areata therapy?J Edelkamp , T Rouille , J Kim , A Rossi , F Jimenez , R Paus, I Catlett and M BertoliniJ Invest Dermatolread the full story
download poster		European Society for Dermatological Research Abstract no. 061
2021Laser-capture microdissection coupled to metagenomics: A powerful method for analysis of the HF microbiome.M Lousada, J Edelkamp, T Lachnit, M Fehrholz, TG Bosch and R PausJ Invest Dermatolread the full story
download poster		European Society for Dermatological Research Abstract no. 322
2021A novel cosmetic anti-hair loss approach: An extract of Leontopodium alpinum inhibits catagen developmentJ Edelkamp, R Campiche, A Le Riche, A Fernandez, M Gempeler, E Martin and M BertoliniJ Invest Dermatolread the full story
download poster		European Society for Dermatological Research Abstract no. 330
2021Poor perifollicular vascularization is associated with nutrient insufficiency and a quiescent metabolic phenotype in intermediate hair follicles from patients with female pattern hair lossI Piccini, M Sousa, J Edelkamp, F Jimenez, A Rossi, R Paus and M BertoliniJ Invest Dermatolread the full story
download poster		European Society for Dermatological Research Abstract no. 333
2021Sphingosine 1-phosphate receptors are expressed in human scalp hair follicles and their modulation by etrasimod warrants further investigation for management of alopecia areata.I Piccini, M Fehrholz, O Egriboz, L Ponce, JW Adams, CM Crosby, M BertoliniJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 489
2021Human skin organ culture permits to preclinically assess the effects of “UVfree tanning” and “skin lightening” agents on epidermal melanogenesis.M van Lessen , T Biro , J Edelkamp, M Bertolini, R PausJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 540
2021An extract of Leontopodium alpinum prolongs anagen phase in human hair follicles ex vivoR Campiche, A Le Riche, J Edelkamp, E Martin, M Gempeler, M BertoliniJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 575
2021Hair follicle chemosensation: TRPM5 signaling is required for anagen maintenanceA Mardaryev , M van Lessen, FJ Acosta , T Biro, R PausJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 589
2021Pre‐clinical trial platform for assessing the effect of cosmeceutical agents on epidermal melanogenesis in human skin organ culture.M van Lessen, R Alqasemi, J Edelkamp, M Bertolini, R Paus, T BíróExp Dermatol.read the full story
download poster		47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung
Abstract no. P174
2021Probing the morphogenic potential of human hair matrix keratinocytes in generating hair follicle organoids in vitro and ex vivo.I Piccini, K Bakkar, C Collin‐Djangone, J Gherardini, R Paus, M BertoliniExp Dermatol.read the full story
download poster		47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung
Abstract no. P240
2021Application of topical Sandalore increases epidermal dermcidin synthesis in organ‐cultured human skin ex vivo.J Edelkamp, D Pinto, J Chéret, J D B O’Sullivan, F Jimenez, W Funk, C Roessing, V Rippmann, F Rinaldi, R Paus, M BertoliniExp Dermatol.read the full story
download poster		47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung
Abstract no. P241
2021Hair follicle chemosensation: TRPM5 signaling is required for anagen maintenance.A Mardaryev, M van Lessen, F Jimenez Acosta, R Paus, T BíróExp Dermatol.read the full story
download poster		47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung
Abstract no. P245
2021A novel strategy for preventing chemotherapy‐induced permanent alopecia: PPARg signaling modulation protects from cyclophosphamide‐induced bulge stem cell apoptosis and epithelial‐mesenchymal transition ex vivoI Piccini, J Chéret, S Ghatak1, M Alam, J Hardman, H Erdmann, F Jimenez, C Ward, R Paus, M BertoliniExp Dermatol.read the full story
download poster		47th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung
Abstract no. P250
2019Mouse models of alopecia areata: C3H/HeJ mice versus the humanized AA mouse model.A Gilhar, A Keren, R PausJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 080
2019Which characteristics does an optimal animal model for psoriasis need to show?A Gilhar, A Keren, R PausJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 081
2019OR2AT4 activation by a synthetic odorant, stimulates dermcidin production in human hair follicle epithelium and increases follicular resistance to bacterial contamination: A novel antimicrobial folliculitis therapy?J Lehmann, J Cheret, L Ponce, F Jimenez, H Eerdmann, M Bertolini, R PausJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 495
2019Possible role of ILC1 in the pathogenesis of alopecia areata (AA).R Laufer Britva, A Keren, Y Ullmann, R Paus, A GiharJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 516
2019Topical Sandalore®, a specific OR2AT4-stimulating odorant, ameliorates female telogen effluvium: Randomized, double-blinded, placebo-controlled clinical trial.M Bertolini, F Jimenez, E Lopez, M Alam, C Ward, J Cheret, G Westgate, F Rinaldi, R PausJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 609
2019Development of a novel humanized mouse model for atopic dermatitis.A Karen, C Reithmüller, Y Ullmann, R Paus, A GilharJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 661
2019PPARγ stimulation protects from cyclophosphamide-induced hair follicle cytotoxicity and bulge stem cell damage.I Piccini, J Cheret, S Ghatak, M Alam, J Hardmann, H Erdmann, F Jimenez, C Ward, R Paus, M BertoliniJ Invest Dermatolread the full story
download poster		Society for Investigative Dermatology
Abstract no. 909
2019Dermal white adipose tissue secretes hepatocyte growth factor to promote human hair follicle growth and pigmentation.C Nicu, J Hardmann, T Lai, J Pople, R Bhogal, D Ansell, R PausJ Invest Dermatolread the storySociety for Investigative Dermatology
Abstract no. 992