Cosmetic Publications - Page 4 of 4

Comparison of gene expression profiles in human keratinocyte mono-layer cultures, reconstituted epidermis and normal human skin; transcriptional effects of retinoid treatments in reconstituted human epidermis

Cosmetics_cat_publi, Cosmétique, Epidermal regeneration

In order to validate a model for predictive screening of dermatological drugs, we used a customized cDNA macro-array system containing 475 skin-related genes to analyze the gene expression patterns in human keratinocytes from different origins.

Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis

Safety and tolerance

The reconstituted human epidermis model SkinEthic was used to evaluate the phototoxicity of topically applied chemicals.

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