Reference Title EndPoint Method
Reference Title EndPoint Method
CD4TL-0007CD4+ T cells, Th17 cytokine release (anti-CD3/anti-CD28 stimulation)IL-17 release
or other Th17 cytokines
ELISA / EIA
NHEK-0009NHEK, antimicrobial peptide release (cytokine stimulation)beta-defensin 2 release
Elafin release
S100A7 release
ELISA / EIA
NHEK-0010NHEK, chemokine release (cytokine stimulation)CXCL-1 release
IL-8 release
ELISA / EIA
NHEK-0012NHEK, cytokeratin 10 expression (cytokine stimulation)Cytokeratin 10 immunolabelingImmunofluorescence
NHEK-0007NHEK, gene expression (cytokine stimulation)mQPA-NHEK-PSO-16
mQPA-NHEK-PSO-32
mQPA-NHEK-PSO-64
mRNA: e.g. DEFB4, S100A7, CXCL8, KRT10,...
qPCRarray (standard or customized)
RT-qPCR
NHEK-0014NHEK, NF kappaB translocation (cytokine stimulation)NF kappaB translocationImmunofluorescence
NHEK-0022NHEK, STAT3 activation (cytokine stimulation)STAT3 phosphorylation / translocationImmunofluorescence
EPIBA-0006RHE, gene expression (cytokine stimulation)mQPA-NHEK-PSO-16
mQPA-NHEK-PSO-32
mQPA-NHEK-PSO-64
mRNA: e.g. DEFB4, S100A7, CXCL8, KRT10,...
qPCRarray (standard or customized)
RT-qPCR
EPIBA-0007RHE, histology (cytokine stimulation)HistologyHistology (HE staining)
EPIBA-0057RHE, skin innate immunity markers expression (cytokine stimulation)Expression of e.g. S100A7, beta-defensin 2/4, RNAse7IHC
Immunohistofluorescence