Skin Vascularization

in vitro pharmacology – assay catalog

COSMETICS

Hydration and skin barrier	Skin pigmentation
Epidermal regeneration	Oil skin and sebaceous gland
Firmness and cohesion	Slimming effect and adipocyte metabolism
Skin ageing	Skin vascularization
Epidermal protection	Hair growth
Dermal protection	Safety and toxicity

DERMATOLOGY

Psoriasis
Atopic dermatitis
Wound healing and skin regeneration
Acne
Hair growth and alopecia
Skin pigmentation

PHARMA

Immuno-inflammation
Vascularization
Nervous system
Safety and toxicity
Enzyme activity assays

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Reference	Title	EndPoint	Method
Reference	Title	EndPoint	Method
AOSMC-0001	AoSMC, veinotonic activity (basal)	Calcium mobilization	Time-lapse microscopy
ENDOF-0001	HMVEC + NHDF, differentiation/pseudotube formation (basal, pro-angiogenic agents)	Pseudotube formation	Fluorescence / imaging
ENDOF-0002	HMVEC + NHDF, differentiation/pseudotube formation (VEGF stimulation, anti-angiogenic agents)	Pseudotube formation	Fluorescence / imaging
HUVEC-0001	HUVEC, ICAM-1 expression (TNF- alpha stimulation)	ICAM-1 immunolabeling	Immunofluorescence
NHDF-0071	NHDF, VEGF release (basal)	VEGF release	ELISA / EIA

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in vitro pharmacology – assay catalog

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