Alternative (non-animal) methods for cosmetic testing: current status and future prospects – UV-induced effects
Cosmetique, Cosmétique, Protection et défenses cutanées, Safety and toleranceCosmetic ingredients and mixtures of ingredients absorbing UV light (in particular UV filter chemicals used, for example, to ensure the light stability of cosmetics or used in sun protection products) should be tested for acute phototoxic and photogenotoxic potential.
Alternative (non-animal) methods for cosmetic testing: current status and future prospects – Acute toxicity
Cosmétique, Cosmetique, Protection et défenses cutanées, Safety and toleranceFrom the regulatory point of view, the main objective of acute toxicity testing is basically to classify chemicals according to their intrinsic toxicity
Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis
Protection et défenses cutanées, Safety and toleranceThe reconstituted human epidermis model SkinEthic was used to evaluate the phototoxicity of topically applied chemicals.