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in vitro pharmacology – assay catalog

COSMETICS

Hydration and skin barrier	Skin pigmentation
Epidermal regeneration	Oil skin and sebaceous gland
Firmness and cohesion	Slimming effect and adipocyte metabolism
Skin ageing	Skin vascularization
Epidermal protection	Hair growth
Dermal protection	Safety and toxicity

DERMATOLOGY

Psoriasis
Atopic dermatitis
Wound healing and skin regeneration
Acne
Hair growth and alopecia
Skin pigmentation

PHARMA

Immuno-inflammation
Vascularization
Nervous system
Safety and toxicity
Enzyme activity assays

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Reference	Title	EndPoint	Method
Reference	Title	EndPoint	Method
NHEK-0043	NHEK, ERK1/2 activation (OSM stimulation)	*** (must be login)	*** (must be login)
NHEK-0293	NHEK, expression of genes regulated by Nrf2 transcription factor (basal)	*** (must be login)	*** (must be login)
NHEK-0306	NHEK, FoxO1 translocation (basal)	*** (must be login)	*** (must be login)
NHEK-0067	NHEK, GAG neosynthesis (basal)	*** (must be login)	*** (must be login)
NHEK-0181	NHEK, gene expression (basal)	*** (must be login)	*** (must be login)
NHEK-0007	NHEK, gene expression (cytokine stimulation)	mQPA-NHEK-PSO-16 mQPA-NHEK-PSO-32 mQPA-NHEK-PSO-64 mRNA: e.g. DEFB4, S100A7, CXCL8, KRT10,...	qPCRarray (standard or customized) RT-qPCR
NHEK-0038	NHEK, gene expression (cytokine stimulation)	mQPA-NHEK-AD(2)-16	qPCRarray (standard or customized) RT-qPCR
NHEK-0159	NHEK, gene expression (PMA stimulation)	*** (must be login)	*** (must be login)
NHEK-0090	NHEK, gene expression (poly (I:C) + IL-1 alpha stimulation)	*** (must be login)	*** (must be login)
NHEK-0163	NHEK, gene expression (Poly(I:C) stimulation)	*** (must be login)	*** (must be login)
NHEK-0222	NHEK, gene expression (zymosan stimulation)	*** (must be login)	*** (must be login)
NHEK-0073	NHEK, gene expression - dermo-epidermal junction markers (basal)	*** (must be login)	*** (must be login)
NHEK-0076	NHEK, gene expression - epidermal adhesion markers (basal)	*** (must be login)	*** (must be login)
NHEK-0301	NHEK, gene expression, detoxification profile (basal)	*** (must be login)	*** (must be login)
NHEK-0193	NHEK, glucose consumption (basal)	*** (must be login)	*** (must be login)

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in vitro pharmacology – assay catalog

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