Comparative analysis of original face and skin-warped average face images for the scoring of skin attributes
Cosmetics, Cosmetics, CosmétiqueIn the cosmetic field, claim substantiations face several challenges.One that could seem trivial is illustrating the performance of a product. With the growing awareness of subjects’ image rights and the implementation of more regulations to protect personal data, presenting the effects of a product using the very image of a subject becomes increasingly complicated.
Neryl acetate, the major component of Corsican Helichrysum italicum essential oil, mediates its biological activities on skin barrier
Barrière cutanée et hydratation, Cosmetics, Cosmetics, Cosmétique, Expression de gènes, Skin barrier and hydrationHelichrysum italicum (Roth) G. Don subsp. italicum (H. italicum italicum) from the Asteraceae family grows on dry, rocky or sandy ground around the Mediterranean Basin and is commonly known as the everlasting plant.
Evaluation of a new connected portable camera for the analysis of skin microrelief and the assessment of the effect of skin moisturisers
Cosmetics, Cosmetics, CosmétiqueThe skin surface roughness is an indicator of interest for dermatology and cosmetology. Increased in xerotic skin or irritation, it is one of the most common frequent dermatological disorders.
Analysis of correlation and construction of a predictive model of skin transparency using parameters from digital images of the face
Cosmetics, Cosmetics, CosmétiqueSkin transparency is a cosmetic asset highly considered by Asian women.
Resulting from complex light interactions within the skin, but still not fully understood, there is no simplemethod to measure it objectively.
A novel clinical method to measure skin staining reveals activation of skin damage pathways by cigarette smoke
Cosmetics, Cosmetics, CosmétiqueAndrogens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line.
Acne, Peau grasse, hyperséborrhée et séborégulation, Sebaceous gland regulationAndrogens are key regulators of sebaceous function... A link between mTOR and androgen signaling has previously been reported...as well as a link between these processes and lipid synthesis...Here we aimed at confirming that DHT-induced lipid synthesis/accumulation is at least in part dependent on mTOR activation in the SEBO662AR cell line and that the autophagic process is consequently modified by the androgenic treatment.
Pollution and epigenetics: Histone H3 modifications in keratinocytes after exposure to urban dust and Benzo(a)pyrene
Cosmetics, Cosmetics, Cosmétique, Skin protection and immune defense systemIn this work, human epidermal keratinocytes were used to study the effects of urban dust and benzo(a)pyrene on the epigenetic pattern of the histone H3 protein. The assay was then used to screen a series of plant extracts in order to find cosmetic actives to protect the skin against air pollution.
Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin
Barrière cutanée et hydratation, Médecine vétérinaire, Skin barrier and hydration, Veterinary medicineFilaggrin (FLG) and corneodesmosin (CDSN) are two key proteins of the human epidermis.
Pseudomonas aeruginosa flagellum is critical for invasion, cutaneous persistence and induction of inflammatory response of skin epidermis
Cosmétique, Microbiome cutané, Skin microbiomePseudomonas aeruginosa, an opportunistic pathogen involved in skin and lung diseases, possesses numerous virulence factors, including type 2 and 3 secretion systems (T2SS and T3SS) and its flagellum, whose functions remain poorly known during cutaneous infection.
Effects of different kinds of pollutants on the lipidic metabolism of human sebocytes and protective effects of a new macroalgae culture extract
Cosmetics, Peau grasse, hyperséborrhée et séborégulation, Sebaceous gland regulation, Skin protection and immune defense systemSebocytes lipid production are stimulated by pollutants. Ame acts by protecting epidermal cells, human sebocytes and skin from urban dust.
A Compensating Skin Care Complex Containing Pro-xylane in Menopausal Women: Results from a Multicentre, Evaluator-blinded, Randomized Study
Cosmetics, Cosmetics, CosmétiqueIn addition to the natural process of skin aging, the skin of women is significantly impacted during and after menopause.
New biological effects of Aphloïol
Cosmetics, Cosmétique, Skin barrier and hydrationIn the present study, we identified new properties of Aphloïol (syn. mangiferin) in improving skin barrier function, especially by promoting keratinocyte differentiation, synthesis of transmembrane glycoprotein and lipid neosynthesis.
Rab11a Is Essential for Lamellar Body Biogenesis in the Human
Barrière cutanée et hydratation, Skin barrier and hydrationMost of the skin barrier function is attributable to the outermost layer of the epidermis, the stratum corneum, which is composed of flattened, anucleated cells called corneocytes surrounded by a lipid-enriched lamellar matrix.
Exploration of scalp surface lipids reveals squalene peroxide as a potential actor in dandruff condition
CheveuxDandruff is a common but complex disorder with three major contributing factors: (1) individual predisposition, (2) scalp sebum and (3) Malassezia yeast colonization.
Effect of C-xyloside on morphogenesis of the dermal epidermal junction in aged female skin. An ultrastuctural pilot study
Cosmetics, Cosmétique, Skin ageingThese data suggest that topical C-xyloside application in vivo may be efficient in inducing a better dermal-epidermal cohesion when such a junction is deficient, as is the case in photo-aged or chronologically aged skin. Moreover, a statistically significant increase in CD44 expression was noted in the epidermis of C-xyloside-treated compared to the placebo treated skin areas.
Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (Sinetrol) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-Phosphodiesterase (PDE)
Adipocyte metabolism, Cosmetics, CosmétiqueThe present study investigated the lipolytic (break of fat stored) effect of a citrus-based polyphenolic dietary supplement (SINETROL) at human adipocytes (ex vivo), body fat (clinical) and biochemical levels (inhibition of phosphodiesterase).
Reduced expression of the adhesion protein tensin1 in cultured human dermal fibroblasts affects collagen gel contraction
Cosmetics, Cosmétique, Skin ageingtensin1 plays an important role in cell-matrix interaction and that a reduced expression might contribute to the dermal alterations observed during skin ageing
Alternative (non-animal) methods for cosmetic testing: current status and future prospects – UV-induced effects
Cosmetics, Cosmétique, Safety and toleranceCosmetic ingredients and mixtures of ingredients absorbing UV light (in particular UV filter chemicals used, for example, to ensure the light stability of cosmetics or used in sun protection products) should be tested for acute phototoxic and photogenotoxic potential.
Alternative (non-animal) methods for cosmetic testing: current status and future prospects – Acute toxicity
Cosmetics, Cosmétique, Safety and toleranceFrom the regulatory point of view, the main objective of acute toxicity testing is basically to classify chemicals according to their intrinsic toxicity
Comparison of gene expression profiles in human keratinocyte mono-layer cultures, reconstituted epidermis and normal human skin; transcriptional effects of retinoid treatments in reconstituted human epidermis
Cosmetics, Cosmétique, Epidermal regenerationIn order to validate a model for predictive screening of dermatological drugs, we used a customized cDNA macro-array system containing 475 skin-related genes to analyze the gene expression patterns in human keratinocytes from different origins.